ea0036oc4.3 | Oral Communications 4 | BSPED2014
Meso Muriel
, Katugampola Harshini
, Aquilina Joe
, Allen Rebecca
, Marleen Shemoon
, Storr Helen
, Dunkel Leo
, Charalambous Marika
Background: Delta-like homologue 1 (DLK1) encodes a transmembrane protein, which may also be secreted into the circulation. Levels are known to rise in maternal serum during late gestation and our genetic studies in the mouse have shown that this DLK1 arises from the conceptus. The cell population that secretes DLK1 into the maternal circulation has not been identified. In humans DLK1 has been shown to be differentially expressed in intrauterine growth restricted (IUGR) when c...